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  • Ive De Smet Lab
    modifications With respect to the latter temporary and reversible phosphorylation of proteins is essential in regulating intracellular biological processes Phosphorylation affects protein folding conformation protein function and the regulation of enzymatic activities defines substrate specificity and influences protein localization complex formation and degradation The mechanistic importance of phosphorylation is obvious from its major influence on various cell functions such as signal transduction cell division cell differentiation and metabolic maintenance During the last ten years Arabidopsis thaliana has been proven to be an efficient model plant to study plant growth and development but time has come to investigate signaling cascades in crop species such as maize wheat and rice species that are currently also under investigation Phosphatases and Kinases While the knowledge on post translational regulation through transient phosphorylation in plants is growing because of its crucial importance in plant molecular networks it remains an underexplored and challenging area Read more Phosphoproteomics We apply a gel free phosphoproteomics pipeline to different biological systems Arabidopsis cell suspension cultures liquid Arabidopsis seedling cultures and the monocot leaves Read more Projects Ive De Smet Group Members Publications Ive De Smet Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme

    Original URL path: http://www.psb.vib-ugent.be/functional-phosphoproteomics (2016-04-26)
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  • Jenny Russinova Lab
    light grown morphology when grown in dark Like their animal counterparts brassinosteroids regulate the expression of numerous genes impact the activity of complex metabolic pathways contribute to the regulation of cell division and differentiation and help control overall development Brassinosteroids regulate photomorphogenesis etiolation and cell expansion Brassinosteroids have a broad spectrum of activities that have a positive effect on the quantity and quality of crops and they increase plant resistance to stress and pathogens Read more Integration and Specificity of Brassinosteroid Signaling Recent studies revealed that brassinosteroid signaling interacts and shares components signaling hubs with a number of other signaling pathways Read more Endocytosis and Brassinosteroid Signaling Growing evidence suggests that plants have adapted endocytosis for signal transduction and use mechanisms similar to those of animals to regulate receptor internalization because for example endocytic trafficking plays a role in the regulation of brassinosteroid signaling Read more Chemical Genetics Genetic studies of brassinosteroid signaling and of its interplay with endocytosis are hampered by gene redundancy the very dynamic nature of endomembrane trafficking and the high degree of lethality of the genes encoding endomembrane components Read more International Projects An overview of the international projects we are or were involved in Read more News You will find the latest news here Read more Joining the Lab Scientists interested in joining our research group for Postdoctoral or PhD projects can contact This email address is being protected from spambots You need JavaScript enabled to view it Postdocs are expected to apply for independent fellowships Projects Jenny Russinova Group Members Lab Members and Alumni Group in Action Publications Jenny Russinova Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme Lab Dirk Inzé Lab Frank Van Breusegem Lab Geert De Jaeger Lab Ive De Smet Lab Jenny Russinova Lab Lieven

    Original URL path: http://www.psb.vib-ugent.be/brassinosteroids (2016-04-26)
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  • Lieven De Veylder Lab
    DNA has been replicated correctly and without damage years of research have revealed many differences between the ways animals and plants control their cell cycle The group aims to understand how cell cycle control genes drive plant cell proliferation and to elucidate how cell division control interacts with different aspects of plant development such as morphogenesis architecture and growth both under control and stress conditions Identifying the underlying mechanisms that control cell division might open opportunities to adjust plant size yield and architecture Mitosis or Endoreduplication In many plant species exit from the division cycle is accompanied by the onset of endoreplication representing a modified version of the normal mitotic cell cycle during which DNA is replicated without mitosis Endoreplication typically occurs in large metabolically active and highly specialized cells although it can be found as well in cells that do not match this description Read more DNA Integrity Checkpoint Control Genome integrity of cells is threatened by DNA damage that is consequence of environmental or endogenous origins To cope with these stress conditions cells have developed a set of surveillance mechanisms that monitor the status and structure of DNA during cell cycle progression Read more Diatom Cell Division Diatoms are predominant unicellular organisms in marine and freshwater ecosystems that encounter intense variations in their environment Thus in order to survive diatoms must be able to control their cell and life cycle rhythms to a variety of different conditions Read more Projects Lieven De Veylder Group Members Publications Lieven De Veylder Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme Lab Dirk Inzé Lab Frank Van Breusegem Lab Geert De Jaeger Lab Ive De Smet Lab Jenny Russinova Lab Lieven De Veylder Lab Mieke Van Lijsebettens Lab Moritz Nowack Lab Sofie Goormachtig Lab Steven Maere

    Original URL path: http://www.psb.vib-ugent.be/cell-cycle (2016-04-26)
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  • Mieke Van Lijsebettens Lab
    the DNA template more accessible for the elongating RNA PII We study the upstream regulation target gene specificity downstream pathways and environmental interaction of these complexes Energy use in plants is an important component of yield stability in the field under varying environmental conditions Epilines were selected in canola and rice using energy use efficiency and seed yield in the field as parameters Transcriptome methylome and histone modifications are analyzed in order to identify underlying putative epialleles and networks A maize transformation platform is in place for basic and translational research The transformation efficiency has been improved and the toolbox extended which allows a higher throughput of constructs and makes the system more versatile Chromatin in Growth Chromatin modification enzymes or complexes monoubiquitinate methylate acetylate or phosphorylate histones which impact the accessibility of the genomic DNA in processes such as transcription replication recombination and mitotic condensation Nelissen et al 2007 Read more Epilines Plants use epigenetic regulatory mechanisms to coordinate changes in gene expression in order to rapidly respond to the environment Read more Leaf Growth Mutants The leaf is an excellent experimental system to study genetic epigenetic and environmental factors that impact growth Indeed upon initiation and dorsoventral patterning leaves grow mainly in two dimensions by cell proliferation and cell expansion to reach a species specific size and shape Read more Tetraspanins in Development In multicellular organisms patterning processes generate axes in the primary body plan create domains upon organ formation and lead to differentiation of functional tissues and cell types Van Lijsebettens and Van Montagu 2005 Read more Maize Transformation Maize is a monocotyledonous model because of the availability of genomics and genetics resources It is one of the most important crops worldwide and is used for food feed and biofuel production Read more Plant Transgenesis The special

    Original URL path: http://www.psb.vib-ugent.be/chromatin-and-growth (2016-04-26)
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  • Moritz Nowack Lab
    organisms PCD has adopted a multitude of functions in physiological and pathological development In both animals and plants defects in the molecular control of PCD can cause severe developmental aberrations and diseases The significance of PCD for human health has been recognized decades ago and today we have a detailed understanding of the molecular regulation of apoptosis and some other forms of animal PCD In plants however we still know comparatively little about PCD despite the fact that different forms of PCD occur throughout plant life and many of them are critical for plant health and fitness as well as for successful growth and reproduction Our lab is interested in the molecular control of plant PCD during vegetative and reproductive development Dozens of different cell types tissues and organs execute a tightly regulated actively controlled cell death in the course of their differentiation and development We identified several commonly expressed plant cell death markers suggesting that a conserved PCD core machinery controls initiation and execution of cell death in diverse developmental contexts Using cutting edge molecular cell and systems biology approaches we are unravelling the mechanisms that control preparation initiation and execution of plant PCD as an inherent part of cellular differentiation Most research is performed in the framework of vegetative and reproductive development of the model plant Arabidopsis thaliana but additionally we investigate PCD during fertilization and seed set of maize Zea mays as an important seed producing crop plant Projects Moritz Nowack Group Members Lab Members and Alumni Group in Action Publications Moritz Nowack Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme Lab Dirk Inzé Lab Frank Van Breusegem Lab Geert De Jaeger Lab Ive De Smet Lab Jenny Russinova Lab Lieven De Veylder Lab Mieke Van Lijsebettens Lab Moritz Nowack Lab

    Original URL path: http://www.psb.vib-ugent.be/programmed-cell-death (2016-04-26)
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  • Sofie Goormachtig Lab
    her team studies how plant roots interact with neighboring organisms in a mutualistic commensalistic or parasitic way In particular we are interested in deciphering the signaling mechanisms that guide interactions between roots and endo rhizospheric organisms Strigolactone Action in the Rhizosphere Plants secrete a variety of compounds inside the rhizosphere to control the interactions with surrounding organisms Read more Root Endosphere and Rhizosphere Plant roots are colonized by vast amounts of microorganisms of which many facilitate plant growth Read more Nutrient Availability and Nodule Development Nutrient availability has a great impact on root organ development such as on lateral root development and legume nodule development Read more Projects Sofie Goormachtig Group Members Group in Action Publications Sofie Goormachtig Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme Lab Dirk Inzé Lab Frank Van Breusegem Lab Geert De Jaeger Lab Ive De Smet Lab Jenny Russinova Lab Lieven De Veylder Lab Mieke Van Lijsebettens Lab Moritz Nowack Lab Sofie Goormachtig Lab Steven Maere Lab Tom Beeckman Lab Yves Van de Peer Lab Wout Boerjan Lab About PSB PSB Missions The Department Infrastructure Core Facilities International Projects Publications News Seminars Research Groups Alain Goossens Lab Ann Depicker

    Original URL path: http://www.psb.vib-ugent.be/rhizosphere (2016-04-26)
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  • Steven Maere Lab
    fully sequenced genomes and the development of high throughput functional genomics technologies we now have the tools to look at the molecular biology of an organism from a systemic viewpoint Systems biology is a dynamic and highly interdisciplinary field requiring input from biology as well as engineering physics and mathematics One of our main interests is the development of methods to analyze functional genomics data and integrate them in models that reflect the regulatory wiring and modularity of biological systems and ultimately predict their behavior We are also developing user friendly computational tools to assist wet lab researchers in the interpretation of large scale datasets and biological networks Projects Steven Maere ESB Website Group Members Publications Steven Maere Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme Lab Dirk Inzé Lab Frank Van Breusegem Lab Geert De Jaeger Lab Ive De Smet Lab Jenny Russinova Lab Lieven De Veylder Lab Mieke Van Lijsebettens Lab Moritz Nowack Lab Sofie Goormachtig Lab Steven Maere Lab Tom Beeckman Lab Yves Van de Peer Lab Wout Boerjan Lab About PSB PSB Missions The Department Infrastructure Core Facilities International Projects Publications News Seminars Research Groups Alain Goossens Lab Ann Depicker

    Original URL path: http://www.psb.vib-ugent.be/evolutionary-systems-biology (2016-04-26)
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  • Tom Beeckman Lab
    numerous interactions between plants and their environment take place The diversity of functions and broad range of interactions with the environment render the biology of roots complicated During the last ten years Arabidopsis thaliana has been proven to be an efficient model plant to study root development and time has come to extrapolate the obtained insights to crop species such as maize a species that is currently also under investigation Read more Lateral Root Initiation In Arabidopsis thaliana Lateral Root Initiation LRI is hallmarked by coordinated asymmetric divisions in adjacent xylem pole pericycle cells Similar to many developmental processes it is strongly regulated by the plant hormone auxin Read more Vascular Tissue Development Plants have the remarkable potential for indeterminate post embryonic growth Following their specification in the early embryo tissue specific precursor cells first establish tissues and later maintain these for indeterminate post embryonic development Despite their importance mechanisms underlying tissue establishment and indeterminacy are virtually unknown Read more LRI in Crop Plants Within the angiosperms major differences in root architecture between dicotyledonous and monocotyledonous plants exist We are working on the genetic and molecular mechanisms involved in the development of the root system in major crop species Read more LRI Transcriptomics LRI datasets were compiled and integrated in the eFP browser online tool Read more FACS General information and technical specificities about the EPICS ALTRA Fluorescent Activated Cell Sorting FACS machine This system allows rapid separation of large numbers of specific cell populations from protoplasted tissues with high purity recovery and yield Read more TEM The Transmission Electron Microscopy TEM facility located on the campus Ledeganck of the UGent is providing expertise in the use and application of transmission electron microscopy to serve biological or biomedical sciences Read more Chemical Biology Chemical biology is a research approach that

    Original URL path: http://www.psb.vib-ugent.be/root-development (2016-04-26)
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