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  • Seminars
    seminars 18 Feb Thursday 18 February 2016 02 00pm 03 30pm Organ formation at the shoot apical meristem from morphodynamics to morphomechanics by despe PSB seminars March 2016 04 Mar Friday 04 March 2016 04 00pm 05 30pm Epigenetic control of plant cell reprogramming by despe PSB seminars April 2016 14 Apr Thursday 14 April 2016 11 00am 12 30pm A PI4P driven electrostatic field controls cell membrane identity and signaling in plants by despe PSB seminars 18 Apr Monday 18 April 2016 01 00pm 02 15pm Big Data in the browser Visual Analytics of large scale genome variation data by despe VIB Seminar 29 Apr Friday 29 April 2016 02 00pm 03 30pm A chemical approach to clathrin mediated endocytosis in plants the ups and downs of small molecule target identification by despe PSB seminars May 2016 04 May Wednesday 04 May 2016 02 00pm 03 30pm Molecular networks governing biomass productivity and seed yield by despe PSB seminars 18 May Wednesday 18 May 2016 11 00am 12 30pm Title to be announced by despe PSB seminars 31 May Tuesday 31 May 2016 11 00am 12 30pm Title to be announced by despe PSB seminars PSB Missions The Department

    Original URL path: http://www.psb.vib-ugent.be/seminars/year.listevents/2016/04/26/- (2016-04-26)
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  • Alain Goossens Lab
    cope with various types of stresses but often also have biological activities of high interest to human Yet this impressive metabolic machinery is still hardly exploited mainly because of the limited molecular insight into plant specialized metabolism By using cutting edge functional genomics tools in combination with reverse genetics screenings we aim to identify the essential components acting in the jasmonate signaling network and to characterize the molecular mechanisms driving plant natural product biosynthesis in crop medicinal and model plants Read more Unraveling Jasmonate Signaling Cascades Jasmonates are plant specific signalling molecules found throughout the plant kingdom that steer diverse physiological and developmental processes Read more Gene Discovery Metabolic Engineering To address the current shortcomings for designing effective plant metabolic engineering strategies a functional genomics based technology platform has been created that enables comprehensive investigations and large scale gene discovery programs for metabolism of model and medicinal plants Read more Combinatorial Biochemistry Synthetic Biology Our gene platform will be primarily exploited in a synthetic biology program in which whole pathways leading to the production of valuable known compounds or structurally novel compounds with superior bioactivity will be recreated in heterologous plants or microbial hosts Read more Plants and Human Health Tomato as a Model Food has a great impact on our health and the prevention of disease In a society where food is abundant health depends on a balanced diet The latter depends amongst others on grains vegetables and fruits that are produced safely but also on sufficient intake of vitamins and minerals and access to health promoting molecules Read more Projects Alain Goossens Group Members Lab Members and Alumni Group in Action Publications Alain Goossens Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme Lab Dirk Inzé Lab Frank Van Breusegem Lab Geert De

    Original URL path: http://www.psb.vib-ugent.be/specialized-metabolism (2016-04-26)
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  • Ann Depicker Lab
    promising bioreactors Seeds allow recombinant proteins to stably accumulate at a relatively high concentration and they can be stored at room temperature for long periods of time Both these factors further enable convenient downstream processing Besides antibodies and immunogens in the seed matrix can be used for oral delivery Read more Plant Made Antibodies for Prophylaxis Passive immunization against infections involves the administering of disease specific antibodies Read more Development of Mucosal Vaccines Genetic engineering has allowed the production of subunit vaccines in a whole range of systems each with their own advantages and disadvantages Read more Antibodies as Diagnostic Tools Antibodies are excellent tools for protein research Provided they have the desired affinity specificity and functionality they allow elucidating different aspects of the protein of interest Read more Optimizing Seed Based Production Our group demonstrated that designer simple monomeric dimeric and secretory antibodies devoid of light chains and based on IgAs are efficiently produced in Arabidopsis seeds Read more Protein Purification Protein purification is a crucial aspect of all research projects in the Plant Made Antibodies and Immunogens group Read more Projects Ann Depicker Group Members Lab Members and Alumni Publications Ann Depicker Research Groups Alain Goossens Lab Ann

    Original URL path: http://www.psb.vib-ugent.be/plant-made-antibodies (2016-04-26)
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  • Bruno Cammue Lab
    Fungus Yeast Unit respectively Only the first unit is associated to the VIB Department of PSB and as such further described below The Fungus Yeast Unit studies the mode of action of bioactive peptides including PDFs and small molecules and uses yeast platforms as model systems for higher eukaryotes In our Plant Unit the discovery of different types of PDFs in Arabidopsis thaliana has significantly stimulated our research on their expression and function For example the discovery of the plant defensin AtPDF1 2a and the corresponding signaling pathways involved in its induction broadened the general insight in induced defense mechanisms in plants The corresponding gene is now world wide used as a marker for ethylene jasmonate controlled responses in plants To support this research different molecular tools and approaches have also been developed optimizing plant transformation and molecular breeding Current research is still focussing on 320 PDF like peptides in Arabidopsis using genome wide approaches such as the RNAseq technology primarily aiming at discovering their in planta role This research is recently broadened to other types of stress induced peptides SIPs Our expertise on resistance mechanisms mainly in A thaliana and focusing on resistance to necroptrophic fungi allowed us to successfully use this model plant as a source of resistance traits against agronomically important crops diseases e g Botrytis cinerea in tomato Fusarium oxysporum in banana Cercospora beticola in sugarbeet Cochliobolus heterostrophus in corn Based on the same expertise some years ago we also initiated research on defense mechanisms induced by biocontrol organisms the so called induced systemic response ISR This research is based on transcriptome studies both in a model plant A thaliana and in crops e g tomato lettuce involves both biotic and abiotic biocontrol agents and is mainly directed to different necroptrophic pathogens Bruno Cammue is a

    Original URL path: http://www.psb.vib-ugent.be/plant-fungi-interactions (2016-04-26)
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  • Daniel Van Damme Lab
    formative asymmetric divisions to establish new organs In the majority of higher plant cells both proliferative and formative division planes are determined by the formation of a plant specific cytoskeletal structure termed the preprophase band PPB This structure encircles the premitotic nucleus and determines the future division plane long before the cell actually divides The PPB is however only a transient structure as it disappears prior to nuclear envelope breakdown and its exact function in establishing the future division plane remains still not fully understood Read more Aurora Kinases and Division Plane Determination Alpha aurora kinases play a major role in determining the orientation of the division plane in various formative divisions throughout plant development Van Damme et al 2011 Read more The TPLATE Complex and Endocytosis TPLATE has been identified as a subunit of an octameric protein complex driving clathrin mediated endocytosis at the plasma membrane in plant cells working either independently or in concert with the evolutionary conserved AP2 heterotetrameric adaptor protein complex Read more Microscopy Infrastructure Overview of all microscopes in the department Read more Confocal Movies Selection of confocal movies from previous and current research projects Read more Selected Group Publications List of publications from the Advanced Live Cell Imaging Group Read more Information for PhD Candidates People interested in joining the group to work on a PhD project are always welcome to contact us This email address is being protected from spambots You need JavaScript enabled to view it Read more Projects Daniel Van Damme Group Members Lab Members and Alumni Group in Action Web Links Publications Daniel Van Damme Research Groups Alain Goossens Lab Ann Depicker Lab Bruno Cammue Lab Daniel Van Damme Lab Dirk Inzé Lab Frank Van Breusegem Lab Geert De Jaeger Lab Ive De Smet Lab Jenny Russinova Lab Lieven De

    Original URL path: http://www.psb.vib-ugent.be/advanced-live-cell-imaging (2016-04-26)
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  • Dirk Inzé Lab
    underpinning crop yield and plant organ size partly because of its multifactorial nature in which many physiological processes such as photosynthesis water mineral uptake and stress tolerance determine the resources available to produce new cells tissues and organs Albeit plant growth and stress tolerance are obviously high complex processes novel approaches collectively called systems biology allow us to better understand this complexity It is our ambition to decipher the molecular networks underpinning yield and organ growth both under standard as well as mild drought stress conditions in Arabidopsis and the C4 crop maize Systems biology will ultimately provide a holistic view enabling the optimalization of plant productivity either by advanced plant breeding or genetic engineering Organ Size Regulation Molecular systems governing leaf growth from genes to networks Size control of multicellular organisms poses a longstanding biological question that has always fascinated scientists Currently the question is far from being resolved because of the complexity of and interconnection between cell division and cell expansion two different events necessary to form a mature organ Read more Unravel Leaf Growth Computational approaches to unravel leaf growth High throughput technologies generate huge amounts of data representing the active components of the cell e g genes proteins metabolites and the interactions between them in particular developmental stages tissues or environments Focusing on leaf growth we develop and apply computational approaches to construct networks of the players that are relevant to growth and development of the leaf to better understand the regulatory processes involved Read more Drought Tolerance Systems biology of drought tolerance in Arabidopsis With the rapidly growing world population and the increasing demand for food the importance to stabilize plant yield even under adverse environmental conditions is evident Read more Maize Leaf Development Translational research maize leaf and ear development The maize leaf offers

    Original URL path: http://www.psb.vib-ugent.be/systems-biology-of-yield (2016-04-26)
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  • Frank Van Breusegem Lab
    tolerance a major objective in plant biotechnology research Oxidative Stress Reactive Oxygen Species ROS causing oxidative stress were long considered as harmful by products of diseased metabolism However recently they have emerged as important regulators of plant stress responses Read more Ghent BioEconomy The Oxidative Stress and Signaling group participates in the UGent Multidisciplinary Research Project Biotechnology for a Sustainable Economy One of the cornerstones of this project is the metabolic engineering of plants to improve their properties for the biobased economy Read more Joining Forces We are engaged in research agreements with Bayer BioScience NV the Flemish agro biotech innovation center of Bayer CropScience Through this collaboration the researchers aim to elucidate the mechanisms that indicate how plants handle stress Read more Degradomics Proteases play crucial roles in stress acclimation and cell death in plants Degradomics mapping the substrates and cleavage sites of proteases was only recently applied to plants but will be crucial to understand the impact of proteases during stress acclimation and cell death Read more News You will find the latest news here Read more Projects Frank Van Breusegem Group Members Lab Members and Alumni Publications Frank Van Breusegem Research Groups Alain Goossens Lab Ann Depicker

    Original URL path: http://www.psb.vib-ugent.be/oxidative-stress-signalling (2016-04-26)
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  • Geert De Jaeger Lab
    lies affinity purification of macromolecular complexes The advantage of this approach is that interactions are discovered in situ These tools are applied to gather knowledge on cell growth and proliferation control in plants and as such discover new approaches for the engineering of plant growth Cell growth and proliferation play a key role in plant growth and development We want to map protein complexes involved in the regulation of cell growth and proliferation and analyse their function The tools to accomplish this are described in more detail below Protein Complex Isolation Protein protein interactions as they appear in functional protein complexes have been studied in high throughput fashion in yeast through yeast 2 hybrid on the one hand and affinity purification followed by mass spectrometry AP MS on the other hand We have developed a unique AP MS platform for protein complex isolation from plant cells Read more AP MS Platform Service We offer the plant research community and companies access to our protein complex purification platform Purifications under research service agreement are performed based on well etablished protocols for complex purification from either the Arabidopsis cell suspension cultures PSB D L or Col 0 seedlings We have recently been able to show that our complex purification technology performs equally well in crop species such as corn or rice Read more Technology Transfer to Crop Species We have recently been able to show that our complex purification technology performs equally well in crop species such as corn or rice We have also started AP MS development in wheat Read more Chromatin Complex Isolation Analysis of sequence specific protein DNA interactions is critical for understanding how chromatin is organized and regulates genetic and epigenetic gene expression We are developing an in situ method to detect protein DNA interactions for a genomic

    Original URL path: http://www.psb.vib-ugent.be/functional-interactomics (2016-04-26)
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